I would think Browns and Lakers would be suspect. Not so much salmon and (to a lesser extent) bows.
Anything that eats gobies is taking in concentrated toxins filtered out of the lake water by the zebra mussels the gobies eat.
Browns and (especially) lakers hang out in the goby zone much more often, and fatten up snacking on goby morsels.
Even with those, I would guess cutting the fat out of the filets would get rid of most of the harmfiul stuff...
Not specific to Lake O, finger lakes or anything else would have similar issues - anywhere with fish that eat the mussels.