i typically run 20 lb mono in spring and fall,i use 25 lb in fall,there teeth and jaws harden up in fall,on my reels with all mono i just use 25 lbs,so i dont have to change and waste alot of mono,but my lead core and copper i switch,50 lb and up you will loose action on your lures,makes a big difference,salmon arent as line conciuos as trout are,trout can even see the 25 lb mono,if you use 50 lb mono get the cajin color,for some reason they dont see the red line as easy